Journal: Archives of Medical Science : AMS
Article Title: Therapeutic potential of mesenchymal stem cells in cisplatin-induced acute kidney injury via ASK-1/TXNIP pathway modulation
doi: 10.5114/aoms/193707
Figure Lengend Snippet: Immunohistochemical staining of VEGF of renal cortex sections at magnification ×400, bar 25 µm. A – Immunohistochemical-stained kidney sections of control group showing strong reaction of VEGF protein expression in the renal cortex. B – Immunohistochemical-stained kidney sections of AKI group showing significant reduction in the expression of VEGF in renal medulla. C – Immunohistochemical-stained kidney sections for VEGF protein expression of FUR group showing mild increase in the expression of VEGF in renal cortex. D – Immunohistochemical-stained kidney sections for VEGF protein expression of MSCs group showing marked increase in the expression of VEGF in renal medulla E – The angiogenic effects of MSC in kidney tissue, expressed as area %. Data were presented as means ± SEM. Each column represented the means ± SEM. The mean variations between the groups using Turkey’s significant difference test. a p < 0.01 vs. control, b p < 0.01 vs. cisplatin induced acute kidney injury cells, c p < 0.01 vs. furosemide treated cells
Article Snippet: Hematoxylin and eosin (H&E) stain was applied to 5 μm sections of paraffin-embedded renal tissues for histological investigation [ ], using anti-VEGF rabbit polyclonal Ab (Boster Biological Technology, Pleasanton, CA, USA, Cat.# PA1080).
Techniques: Immunohistochemical staining, Staining, Control, Expressing